Research Center


Technical Data and Press Releases
Scientific publications on Aphanizomenon flos-aquae

Gitta S. Jensen, PhD., Donald I. Ginsberg, M.S., and Christian Drapeau, MS; Blue-Green Algae as an Immuno-Enhancer and Biomodulator JANA Winter 2001 Vol. 3 No.4: (24 – 30). (Read the full article)

Jensen GS, Ginsberg DI, Huerta P, Citton M, Drapeau C (2000) Consumption of Aphanizomenon flos aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA vol. 2 (3): 50-58. (Read abstract)

Kushak RI, Drapeau C, Van Cott EM, Winter HH (2000) Favorable effects of blue-green algae Aphanizomenon flos-aquae on rat plasma lipids. JANA vol. 2 (3): 59-65. (Read abstract)

Lahitova N, Doupovcova M, Zvonar J, Chandoga J, Hocman G (1994) Antimutagenic properties of fresh-water blue-green algae. Folia Microbiol (Praha), 39(4), pp. 301-3. (Read abstract)

Scientific publications on nutrients found in Aphanizomenon flos-aquae:

Phycocyanin

Romay C, Armesto J, Remirez D, Gonzalez R, Ledon N, Garcia I (1998) Antioxidant and anti-inflammatory properties of C-phycocyanin from blue-green algae. Inflamm. Res. 47: 36-41. (Read abstract)

Romay C, Ledon N, Gonzalez R (1998) Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. Inflamm Res. 47(8):334-8. (Read abstract)

Gonzalez R, Rodriguez S, Romay C, Ancheta O, Gonzalez A, Armesto J, Remirez D, Merino N (1999) Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. Pharmacol Res 39(1):55-9. (Read abstract)

Vadiraja BB, Gaikwad NW, Madyastha KM (1998) Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats. Biochem Biophys Res Commun 249(2):428-31. (Read abstract)

Chlorophyll

Dashwood R, Negishi T, Hayatsu H, Breinholt V, Hendricks J, Bailey G. (1998) Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout. Mutat Res. 399(2):245-53. Review. (Read abstract)

Chernomorsky S, Segelman A, Poretz RD. (1999) Effect of dietary chlorophyll derivatives on mutagenesis and tumor cell growth. Teratog Carcinog Mutagen.19(5):313-22. (Read abstract)

Carotenoids

Mayne ST. (1996) Beta-carotene, carotenoids, and disease prevention in humans. FASEB J. 10(7):690-701. (Read abstract)

Shaish, A., Daugherty, A., O’Sullivan, F., Schonfeld, G., and Heinecke, J.W. (1995) Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits. J Clin Invest 96:2075-2082. (Read abstract)

Pryor WA, Stahl W, Rock CL (2000) Beta carotene: from biochemistry to clinical trials. Nutr Rev 58(2 Pt 1):39-53. (Read abstract)

Wang XD, Russell RM. Procarcinogenic and anticarcinogenic effects of beta-carotene. Nutr Rev 57(9 Pt 1):263-72. (Read abstract)

Tavani A, La Vecchia C (1999) Beta-carotene and risk of coronary heart disease. A review of observational and intervention studies. Biomed Pharmacother 53(9):409-16. (Read abstract)

Garewal, HS, et al., (1995) Emerging role of beta-carotene and antioxidant nutrients in prevention of oral cancer, Archives of Otolaryngology 121(2):141-144. (Read abstract)

Polyunsaturated fatty acids
Oomen CM, Feskens EJ, Rasanen L, Fidanza F, Nissinen AM, Menotti A, Kok FJ, Kromhout D. (2000) Fish consumption and coronary heart disease mortality in Finland, Italy and The Netherlands. Am J Epidemiol. 151(10):999-1006. (Read abstract)

von Schacky C. (2000) n-3 fatty acids and the prevention of coronary atherosclerosis. Am J Clin Nutr. 71(1 Suppl):224S-7S. (Read abstract)

Bruinsma KA, Taren DL. (2000) Dieting, essential fatty acid intake, and depression. Nutr Rev. 58(4):98-108. (Read abstract)

Edwards R, Peet M, Shay J, Horrobin D. (1998) Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. J Affect Disord. 48(2-3):149-55. (Read abstract)

Burgess JR, Stevens L, Zhang W, Peck L (2000) Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. Am J Clin Nutr 71(1 Suppl):327S-30S. (Read abstract)

Ziboh VA, Miller CC, Cho Y. (2000) Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr. 71(1 Suppl):361S-6S. (Read abstract)

Ziboh VA. (1989) Implications of dietary oils and polyunsaturated fatty acids in the management of cutaneous disorders. Arch Dermatol. 125(2):241-5 (Read abstract)

Goodfellow J, Bellamy MF, Ramsey MW, Jones CJ, Lewis MJ. (2000) Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol 35(2):265-70. (Read abstract)

Calder PC (1998) Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Braz J Med Biol Res 31(4):467-90.(Read abstract)

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